Moderate riskEurope · Southern EuropeSpain Travel Health Guide
Moderate risk
Spain carries a CDC Level 2 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
Moderate risk
Malaria
None
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure you are up-to-date on all routine vaccines including chickenpox, DTP, flu, MMR, polio, and shingles before traveling.
COVID-19
Stay up to date with COVID-19 vaccines before traveling.
Hepatitis A
Consider hepatitis A vaccination, especially if visiting smaller cities, villages, rural areas, or planning to eat street food.
Hepatitis B
Hepatitis B vaccine is recommended for unvaccinated travelers under 60, and may be considered for those 60 and older.
Measles
Get fully vaccinated against measles with MMR vaccine at least two weeks before travel. Infants 6-11 months should receive an early dose.
Polio
Polio vaccination is important as poliovirus has been identified in Spain. Adults may need a booster, and unvaccinated travelers should complete the series before travel.
Rabies
Rabies pre-exposure vaccination may be considered for high-risk activities. Rabid dogs are uncommon in Spain and post-exposure vaccines are generally available.
Yellow Fever
Yellow fever vaccine is not recommended and not required for entry to Spain.
Disease risks
Emergency numbers
Police
112
Medical / Ambulance
112
Fire
112
U.S. Embassy
+34-91-587-2200
Spain travel health FAQ
Do I need vaccines to travel to Spain?▼
For travel to Spain, Routine Vaccines, COVID-19, Hepatitis A, Hepatitis B, Measles and Polio are recommended; Rabies and Yellow Fever may be advised depending on your itinerary. Make sure your routine vaccinations (such as MMR, Tdap, polio and seasonal flu) are up to date, and see a travel-health provider about 4–6 weeks before you leave.
Is there malaria in Spain?▼
No — Spain is not considered a malaria-risk destination, so antimalarial medication is not routinely needed. Basic insect-bite precautions are still sensible.
Is it safe to travel to Spain?▼
From a travel-health standpoint, Spain is currently rated moderate risk. Spain carries a CDC Level 2 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
What are the emergency phone numbers in Spain?▼
Key emergency numbers in Spain are Police 112, Medical / Ambulance 112, Fire 112 and U.S. Embassy +34-91-587-2200. Save them before you travel and confirm the current numbers with your accommodation on arrival.
More country guides
AlbaniaLow riskAlbania carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed for direct travel from the US, but is required if coming from countries with yellow fever risk.
AndorraLow riskAndorra carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis B, Measles.
Bosnia and HerzegovinaLow riskBosnia and Herzegovina carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.